Mid ka mid ah tilmaamayaasha muhiimka ah, ee lagu go'aamiyo falanqaynta dhiigga, waa heerka monocytes ee dhiigga. Monocytes waa nooca leukocytes. Kuwani waa unugyada dhiigga ugu weyn ee firfircoon ee keena dhuuxa lafta gaduudan. Iyadoo wadajira dhiigga, monocytes aan qaangaarin waxay galaan unugyada jidhka waxayna u gooyaan macrophages. Hawlaha ugu muhiimsan ee walxahan dhiigga waa burburinta iyo nuugista jeermiska cudurada wadnaha ah ee jidhka ku faafay, iyo tirtiridda haraaga unugyada dhintay. Marka la eego xaqiiqda ah in monosytadu ay qabtaan shaqo masuuliyadeed, waxaa loo yaqaan "jilayaasha jidhka." Waa monosytes kuwaas oo noqda caqabad ku ah samaynta unugyada iyo unugyada kansarka. Intaa waxaa dheer, monocytes waxay ku lug leeyihiin habka Hematopoiesis.
Heerka monocytes ee dhiigga
Si loo ogaado in qiimaha dhiigga ee laga helay falanqaynta (oo ay ku jirto heerka monocytes) u dhiganta caadada, waa lagama maarmaan in la yeesho fikrad ah heerka caadiga ah ee monocytes ee calaamadaha gebi ahaanba.
Qiyaasta monocytes ee dhiigga ku jirta waa 3% ilaa 11% tirada guud ee leukocytes ama qiyaastii 400 unug 1 ml oo dhiig ah (sida dhiigga wareegga ka baxsan xubnaha unugyada hematopoietic). Qiyaasta monocytes ee ku jirta dhiigga haweenka ayaa laga yaabaa in ay ka yar tahay xadka hoose iyo xisaabtana 1% tirada leukocytes.
Sidoo kale heerka unugyada cad waxay ku kala duwan yihiin da'da:
- Nidaamka monocyte ee dhiiga ilmo dhasha ah wuxuu u dhexeeyaa 3% ilaa 12%;
- da'da laba toddobaad ayaa heerkulku gaari karaa 15%;
- ilmaha hal sano jir ah waxaa loo tixgeliyaa inuu yahay 4-10%.
Markay tahay qiyaasta caadiga ah ee monocytes ee dhiigga dhif ah ayaa ka badan 8%.
Isbeddel heerka heerka monocytes ee dhiigga
Kordhinta monocytes
Si kor loogu qaado heerka monocytes ee ilmo, xitaa 10%, takhasuslayaashu waxay u muuqdaan kuwo deggan, maaddaama isbedel noocaan ah la socdo geeddi-socodka dabiiciga ah ee dabiiciga ah ee la xidhiidha carruurnimada, tusaale ahaan, ilkuhu. Ka sarraysa isla qiimaha monocytes marka la barbardhigo heerka caadiga ah ee tijaabada dhiigga ee qof weyn uu muujinayo fashil la'aanta habka wareegga wareegga dhiigga, iyo sidoo kale horumarinta cudurrada faafa, sida:
- qaaxada;
- waraabowga;
- enteritis;
- brucellosis ;
- lupus erythematosus;
- rheumatoid arthritis;
- mycosis, iwm.
Iskudhicida ku jira contentka monocyte waxay muujin kartaa horumarinta habdhiska malignantiga ee jirka. Badanaa korodhka tirada unugyada cad ayaa lagu arkay muddada postoperative. Dumarka, sababaha isbedelkani waa badi hawlaha dumarka.
Yaraynta monocytes
Hoos-u-dhac ku yimaada heerka monocytes waa dhacdo waxoogaa dhif ah marka loo eego kororka tilmaamahan. Taas macnaheedu maaha inay tahay cudurkan. Tusaale ahaan, dumar badan ayaa hoos udhigay monocyde xilliga uurka iyo xilliga umusha ka dib. Waqtigaan waa marka ay sabab u tahay dillaac jidhka ah oo laga yaabo inuu muujiyo dhiig-yaraanta.
Sababaha kale ee caadiga ah ee hoos u dhaca walxaha monocyte ee dhiigga:
- Qaar ka mid ah cudurrada faafa, meesha ugu horeysa, xummad xumo ;
- dhaxaltooyada dhiig-yari;
- soo dhaweynta corticosteroids iyo cytostatics;
- cudurada la xiriira waxyeelada unugyada maskaxda.
Hoos u dhigidda heerka monocytes badanaa waxaa lagu arkaa xilliga qalliinka ka dib inta lagu guda jiro xubinta taranka. Laakiin kiiskani waxa uu sababay dabiici ahaan adoo xakameynaya difaaca jirka ee daroogada si looga hortago in jidhku diido unugyada iyo xubnaha unugyada.
Xaalad waliba, isbeddel ku yimaadda walaxda monocyte ee dhiiga waa sabab loo baarayo baaritaan caafimaad si loo ogaado sababta keentay iyo, haddii loo baahdo, sameyso daweyn ku habboon.