Fluoroquinolones waa antimicrobial kaas oo kiimikooyin loo sameeyay si dabiici ah. Bilowga gelitaanka nolosheenna, qaabka jiilka 2aad ee daroogada ee kooxdan (ofloxacin, ciprofloxacin), ayaa loo tixgeliyaa sanadaha 80aad ee qarnigii 20aad. Muuqaalkooda kala-duwan waxay ahaayeen tallaabooyinka ugu ballaaran ee ficillada ka soo horjeeda microbes, bakteeriyada, iyo sidoo kale heerka sare ee nuugista daroogada ee unugyada jidhka, oo lagu faafiyo bukaanka infekshanka.
Muddo hal sano ah, dunidu waxay ku aragtay fluoroquinolones III iyo IV, kuwaas oo aad u ballaadhanaa marka loo eego cudurrada bakteeriyada (ugu horreyntii pneumococci), jeermisyada, cudurada hurgunka heerarka hurgunka. Mid ka mid ah faa'iidooyinka jiilka ugu dambeeya ee fluoroquinolones waa nuugista firfircoon ee firfircoon.
Antibiyootiko ee kooxda fluoroquinolones, oo si toos ah u galaan jidhka, waxay u dhaqmaan sidan si ay uga hortagaan waxqabadka muhiimka ah ee DNA-gyrase (enzyme ee unugyada microbial, oo ah qayb ka mid ah infekshanka), kaas oo markaa dilaayo microbe.
U raacsanaanta fluoroquinolones
Fluoroquinolones waxay leedahay calaamado balaadhan oo loogu talagalay isticmaalka daaweynta. Iyadoo caawimadeeda, waxaa lagula talinayaa in ay qaadaan tallaabooyin tallaabo tallaabo ah oo loogu talagalay daaweynta cudurrada halista ah, waxay u leeyihiin iswaafajin wanaagsan daawooyinka kale ee bakteeriyada.
Qeybaha Fluoroquinolones
- maadooyinka ugu horreeya ee aan la isticmaalin;
- tan labaad - gram-negative-fluoroquinolones;
- sadexaad - fluoroquinolones respiratory;
- afaraad - neefsashada iyo fluoroquinolones antianaeroboon.
Fluoroquinolones ee isticmaalka ugu dambeeyay:
- ee cudurada mareenka neef-mareenka iyo cudurrada ENT ee kala duwan: boronkiitada, oof-wareenka, sinusitis-ka, caleemaha hore (iyo sidoo kale dhibaatooyin soo noqnoqda oo ku yimaada muddada cudurka noocyo kala duwan);
- cudurrada faafa ee kalyaha, iyo sidoo kale habka jimicsiga: cystitis (dareen-celin iyo daba-dheer), pyelonephritis (xanuun, daba-dheer, iyo dhibaatooyin ka soo baxa noocyadan cudurka);
- oo leh infekshanno mareenka caloosha iyo mindhicirka: Dysentery, salmonellosis, infekshin ku salaysan ulaha xiidmaha, qandhada qandhada;
- sababtoo ah infekshanka maqaarka iyo habka taranka;
- oo leh cudurrada galmada lagu kala qaado: jabtada, chancroid jilicsan;
- daaweynta iyo kahortaga cudurrada kala duwan ee faafa, oo leh difaac daciif ah ama xadgudub ku ah shaqadooda;
- ee dib u soo kabashada jidhka xilliga qalliinka kadib.
Antibiyootiko ee saameynta daawada fluoroquinolones:
- Nidaamka Hematopoietic: Dhiig-yare, yareynta lökositta ee dhiiga (taasoo keenaysa hoos u dhaca difaaca jidhka) iyo trombo-yada (taas oo ka sii darta dhiig-karka);
- mareenka caloosha iyo mindhicirka: xanuunka caloosha, xajmiga, cuntada oo yaraata, muuqaalka lallabbada, dhadhanka dhadhanka afka, marar dhif ah -
bararka xiidmaha; - beerka: waxa sii xumaanaya awoodiisa shaqo;
- Nidaamka dhexe ee neerfayaasha: cagaarsho, hurdo la'aan, walaac, walaac, aragga muuqaalka, xaalado dhif ah - suuxdin, dabacsanaan iyo muuqaalo muuqaal ah;
- oo kulaylka daraaddiisna darfaha dhexdooda ku yaal, oo muuqashadeeduna ay caddaaladdarro ku jirto.
- Nidaamka kaadida: nephritis, isbedel ku dhaca midabka kaadida;
- hawlihii anatomical-ka: naaska nuujinta ee ragga;
- ee lafaha iyo muruqyada: xanuun.