Trombocytopenia waa maqnaan ama heer hoose oo dhiig ah (trombo-yada). Unugyada dhiiga unugyada leh ee unugyada leh ayaa muhiim u ah dhiig-xinjirowga. Trombocytopenia waxay noqon kartaa nolol khatar ah, sababtoo ah waxay sababtaa dhiigbax iyo dhiig-baxa dhiig-baxa ee xubnaha gudaha.
Sababaha xanuunka trombocytopenia
Sababaha xinjirowga trombocytopenia waa mid kala duwan. Xididdada "trompetal" ayaa ka imaan karta dhibaatooyin aan la taaban karin oo dhiigga lagu shubo, taas oo aan ku haboonayn xubinnimada kooxda, ama marka antigen-ka ajinebiga uu galo, tusaale ahaan, fayras. Laakiin badanaaba jidhka bini-aadamka, isbeddelka trombocytopenia ayaa kiciya. Tani waa xaalad aan nidaamyada difaaca jirka aysan "ogeyn" qajaarka caafimaadka qaba, taas oo keenaysa horumarinta unugyada difaaca si loo tirtiro "shisheeye". Haddii trombocytopenia ay la socoto jirro kale, ka dibna waxaa loo yaqaan 'secondary'. Sababtuna waa noocyo kala duwan:
- collagenoses (dermatomyositis, lupus erythematosus ama scleroderma );
- leetemia raaga oo joogto ah (Waldenstrom macroglobulinemia, myeloma);
- cudurrada kelyaha iyo cagaarshow joogtada ah.
Haddii trombocytopenia-da autoimmune-giisa laftiisa uu yahay cudurka halbaxlaha ah, waxaa la yiraahdaa cudurka Verlhof, sidoo kale waxa muhiim u ah unugyada dhiig-yare ee 'trombocytopenia'. Sababaha cudurkan ayaa si aan caadi ahayn loo xaqiijin. Waxyaabaha ka soo horjeeda horumarkiisa, waxaa jira caabuqyo fayras iyo bakteeriya, hawlo qalliin, tallaal, dhaawacyo iyo hordhaca gaaska globulin. 45% kiisaska, xinjirowga trombocytopenia wuxuu u dhacaa si aan caadi aheyn sabab la'aan.
Sababaha loo yaqaan "trombocytopenia"
Trombocytopenia oo waxtar leh ayaa ka dhacda jirka, marka dhuuxa lafdhabarku ma gelin karo xinjiraha ku jira xaddiga ay lagama maarmaan u yihiin wareegga caadiga ah. Sababaha trombocytopenia ee dadka waaweyn waa:
- dhiig-yaraanta dhiig-yarida ;
- TAP-syndrome;
- cudurka myelodysplastic syndrome;
- Myelosclerosis;
- metastases burooyinka qaarkood oo ku jira dhuuxa lafta;
- ficilka kiimikada (tusaale, baasiin).
Waxaa intaa dheer, xinjirowga trombocytopenia wuxuu u muuqdaa mid ka dhalan kara leukemia ba'an, marka uu jiro isbadal qoto dheer oo ka yimaada hematopoiesis, khamriga iyo infekshannada kala duwan (viremia, tuberculosis malarary, bacteremia). Ka roonaanta la'aanta xinjiraha iyo kuwa aan qabin vitamin B12 iyo folic acid. Horumarinta suurtogalka ah ee daaweynta trombocytopenia iyo daaweynta shucaaca ama soo-gaadhista shucaaca.
Sababaha loo yaqaan "thrombocytopenia"
Daawada thrombocytopenia, daawooyinka lidka ku ah waxaa laga soo saaraa antigen-dawo-shisheeye oo lagu xaddiday dusha sare ee jirka, ama marka qaabdhismeedka antigenic ee isbeddellada. Xaaladaha badankood, sababaha noocaan ah ee dhiig-baxa ee dhiig-baxa waa daawooyinka soo socda:
1. Sedatives:
- Meprobamate;
- Phenobarbital;
- Sedormid;
- allyl isopropylbarbituric acid.
2. Alkaloids:
- Quinidine;
- Quinine.
- Antibiotics;
- Oxytetracycline;
- Streptomycin;
- Chloramphenicol;
- Ristocetin.
3. Sulfonamides fayruska ah:
- Sulfidiazine;
- Sulfamethazine.
4. Daawooyinka kale:
- Dinitrophenol;
- potassium iodide;
- Digitoxin;
- Carbamazepine.
Sababaha cudurka trombocytopenia ee bukaanada HIV
Trombocytopenia waxay u muuqan kartaa dadka qaba HIV-ga. Waxaa jira laba sababood oo loo xakameynayo xaaladdan bukaanka:
- Marka hore, waa HIV-du wuxuu ku dhuftey megakaryocytes, taas oo keentay in yaraanta taratiyada.
- Marka labaad, daawooyinka ka caawiya la dagaallanka infekshanku inta badan waxyeello lafta lafta gaduudan ee qofka.