Oxymetazoline iyo kumetazoline waa mukhadarooyin daaweyn leh leh walxo xaddidan, iyadoo ku saleysan nooca dhibco sanka iyo buufinada loo soo saaro si loo yareeyo bararka xuubka xabka. Daawooyinkaan waxaa loo isticmaalaa, badanaaba cudurada neefsashada, oo ay weheliyaan cirridka sanka , iyo sidoo kale otis. Ka feker waxa fiican ee la isticmaalo - oxymetazoline ama xylometazoline, waa maxay khilaafkooda iyo isku midka ay yihiin.
Waa maxay farqiga u dhaxeeya oxymetazoline iyo xylometazoline?
Oxymetazoline iyo xylometazoline waa walxo isku mid ah oo la mid ah kooxda imidazolin. Waxay saameynayaan labada nooc ee soo dhaweeye ee xididdada dhiigga ee ku yaala xuubka sanka (α1 iyo α2 reseptors). Tani waxay bixisaa saameyn dhakhso ah, horumar leh oo ku filan oo muddo dheer ku daweynaya.
Marka la isticmaalo oksymetazoline, hagaajinta neefsashada sanka waxaa la ogaadaa illaa 10-12 saacadood, iyo marka xylometazoline loo isticmaalo, waxoogaa yar ayuu yaraa, ilaa 8 saacadood. Si kastaba ha noqotee, saameyn noocaan oo kale ah ee isticmaalka dheeraadka ah ee daroogada ama daroogada kale waxay keenaysaa in ay dhaawacdo xuubka dheecaanka, illaa qoyaanka. Sidaa darteed, waxaa lagu talinayaa in si joogto ah loogu daboolo muddo ka badan shan maalmood xylometazoline iyo saddex maalmood oo loogu talagalay oxymetazoline.
Farqiga u dhexeeya xylometazoline iyo oxymetazoline ayaa sidoo kale ku jira darnaanta cilladda ka bixida ka dib marka la joojiyo isticmaalka. Sidaas awgeed, jidhka oo ka sii daraya ka dib marka la dhammaystiro daaweynta oxymetazoline ayaa ka yara badan xylometazoline ka dib. Intaas waxaa sii dheer, xylometazoline ayaa si khatar ah looga hortagaa uurka, iyo oxymetazoline waxaa loo oggol yahay in la isticmaalo inta lagu jiro dhalmada ilmaha yar ee qiyaasta daaweynta dhakhtarka.
Caqabadaha caadiga ah ee daroogooyinka waa:
- diabetes mellitus;
- glaucoma xagasha xiranka;
- cudurada qanjirka thyroid;
- cudurada hargabka;
- tufaaxa atrophic .
Marka la eego shuruudaha, waxaa lagu soo gabagabeyn karaa in diyaargarowga sanka ku saleysan oxymetazoline ay ammaan yihiin. Si kastaba ha ahaatee, erayga ugu dambeeya waa inuu ahaado kaliya dhakhtarka ku jira, kaas oo tixgelinaya sifooyinka shakhsiyeed ee jirka bukaanka iyo darnaanta jirroolojiga, waxay samayn kartaa doorasho sax ah.
Diyaargarowga ku salaysan oxymetazoline iyo xylometazoline
Daawooyinka caadiga ah leh walaxda firfircoon xylometazoline waa:
- Halazolin;
- Pharmazoline;
- Otrivin.
Iyadoo ku saleysan oxymetazoline, daawooyinka noocan oo kale ah ayaa la soo saaraa:
- Knoxprey;
- Rinazolin;
- Nazivin.